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1

Progress and prospects in rat genetics: a community view

Aitman, Timothy J, Critser, John K, Cuppen, Edwin, Dominiczak, Anna, Fernandez-Suarez, Xose M, Flint, Jonathan, Gauguier, Dominique, Geurts, Aron M, Gould, Michael, Harris, Peter C

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

2

CD36, insulin resistance, and coronary heart disease

Timothy J Aitman

Journal:

Year:

2001

Language:

english

File:

PDF, 60 KB

english, 2001

3

A CD36 nonsense mutation associated with insulin resistance and familial type 2 diabetes

Frédéric Leprêtre, Francis Vasseur, Martine Vaxillaire, Philipp E. Scherer, Saira Ali, Kenneth Linton, Timothy Aitman, Philippe Froguel

Journal:

Year:

2004

Language:

english

File:

PDF, 2.74 MB

english, 2004

4

Insulin Resistance: The Metabolic Syndrome X : G.M. Reaven and A. Laws (Eds.) John Wiley & Sons, 1999. pp. 374, $145, ISBN: 0–896–03588–3 (hb)

Timothy J. Aitman

Journal:

Clinical Endocrinology

Year:

2000

Language:

english

File:

PDF, 32 KB

english, 2000

5

Isoimmunization against CD36 (glycoprotein IV): description of four cases of neonatal isoimmune thrombocytopenia and brief review of the literature

Brian R. Curtis, Saira Ali, Anne M. Glazier, Douglas D. Ebert, Timothy J. Aitman, Richard H. Aster

Journal:

Transfusion (Wiley)

Year:

2002

Language:

english

File:

PDF, 172 KB

english, 2002

6

Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA

Timothy J. Aitman, Catherine M. Hearne, Marcia A. McAleer, John A. Todd

Journal:

Mammalian Genome

Year:

1991

Language:

english

File:

PDF, 415 KB

english, 1991

7

Additional microsatellite markers for mouse genome mapping

Catherine M. Hearne, Marcia A. McAleer, Jennifer M. Love, Timothy J. Aitman, Richard J. Cornall, Soumitra Ghosh, Andrew M. Knight, Jan-Bas Prins, John A. Todd

Journal:

Mammalian Genome

Year:

1991

Language:

english

File:

PDF, 887 KB

english, 1991

8

Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses

Marcia A. McAleer, Timothy J. Aitman, Richard J. Cornall, Soumitra Ghosh, Jennifer R.S. Hall, Catherine M. Hearne, Jennifer M. Love, Jan Bas Prins, Shoba Ramachandran, Nanda Rodrigues, Nicole H. DeLar

Journal:

Mammalian Genome

Year:

1992

Language:

english

File:

PDF, 391 KB

english, 1992

9

Radiation hybrid mapping of 70 rat genes from a data set of differentially expressed genes

Caroline A. Wallace, Saira Ali, Anne M. Glazier, Penny J. Norsworthy, Danilo C. Carlos, James Scott, Tom C. Freeman, Lawrence W. Stanton, Anne E. Kwitek, Timothy J. Aitman

Journal:

Mammalian Genome

Year:

2002

Language:

english

File:

PDF, 153 KB

english, 2002

10

Molecular basis of theCd36chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism

Anne M. Glazier, James Scott, Timothy J. Aitman

Journal:

Mammalian Genome

Year:

2002

Language:

english

File:

PDF, 958 KB

english, 2002

11

Integrated gene expression profiling and linkage analysis in the rat

Enrico Petretto, Jonathan Mangion, Michal Pravanec, Norbert Hubner, Timothy J. Aitman

Journal:

Mammalian Genome

Year:

2006

Language:

english

File:

PDF, 447 KB

english, 2006

12

10.1038/35016636

Aitman, Timothy J., Cooper, Lisa D., Norsworthy, Penny J., Wahid, Faisal N., Gray, Jennefer K., Curtis, Brian R., McKeigue, Paul M, Kwiatkowski, Dominic, Greenwood, Brian M., Snow, Robert W., Hill, Ad

Journal:

Year:

2000

Language:

english

File:

PDF, 118 KB

english, 2000

13

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

Todd, John A., Aitman, Timothy J., Cornall, Richard J., Ghosh, Soumitra, Hall, Jennifer R. S., Hearne, Catherine M., Knight, Andrew M., Love, Jennifer M., McAleer, Marcia A., Prins, Jan-Bas

Journal:

Year:

1991

File:

PDF, 687 KB

1991

14

10.1038/5013

Aitman, Timothy J., Glazier, Anne M., Wallace, Caroline A., Cooper, Lisa D., Norsworthy, Penny J., Wahid, Faisal N., Al-Majali, Khulood M., Trembling, Paul M., Mann, Christopher J., Shoulders, Carol C

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 714 KB

english, 1999

15

10.1038/84777

Pravenec, Michal, Landa, Vladimir, Zidek, Vaclav, Musilova, Alena, Kren, Vladimir, Kazdova, Ludmila, Aitman, Timothy J., Glazier, Anne M., Ibrahimi, Azeddine, Abumrad, Nada A., Qi, Nianning, Wang, Jia

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 379 KB

english, 2001

16

Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus

Morris, David L, Roberts, Amy L, Witherden, Abigail S, Tarzi, Ruth, Barros, Paula, Whittaker, John C, Cook, Terence H, Aitman, Timothy J, Vyse, Timothy J

Journal:

European Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 335 KB

english, 2010

17

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

Aitman, Timothy J., Dong, Rong, Vyse, Timothy J., Norsworthy, Penny J., Johnson, Michelle D., Smith, Jennifer, Mangion, Jonathan, Roberton-Lowe, Cheri, Marshall, Amy J., Petretto, Enrico

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

18

Distribution and functional impact of DNA copy number variation in the rat

Guryev, Victor, Saar, Kathrin, Adamovic, Tatjana, Verheul, Mark, van Heesch, Sebastiaan A A C, Cook, Stuart, Pravenec, Michal, Aitman, Timothy, Jacob, Howard, Shull, James D

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 452 KB

english, 2008

19

Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension

Pravenec, Michal, Churchill, Paul C, Churchill, Monique C, Viklicky, Ondrej, Kazdova, Ludmila, Aitman, Timothy J, Petretto, Enrico, Hubner, Norbert, Wallace, Caroline A, Zimdahl, Heike

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 291 KB

english, 2008

20

Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats

Aitman, Timothy J., Gotoda, Takanari, Evans, Alison L., Imrie, Helen, Heath, Karen E., Trembling, Paul M., Truman, Hazel, Wallace, Caroline A., Rahman, Ahmadur, Doré, Caroline

Journal:

Nature Genetics

Year:

1997

File:

PDF, 521 KB

1997

21

Reply to “Normalization procedures and detection of linkage signal in genetical-genomics experiments”

Petretto, Enrico, Mangion, Jonathan, Cook, Stuart A, Aitman, Timothy J, Pravenec, Michal, Schulz, Herbert, Fischer, Judith, Hubner, Norbert

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 695 KB

english, 2006

22

A gene harvest revealing the archeology and complexity of human disease

Petretto, Enrico, Liu, Edison T, Aitman, Timothy J

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 210 KB

english, 2007

23

The rat comes clean

Wallace, Caroline A, Aitman, Timothy J

Journal:

Nature Genetics

Year:

2004

Language:

english

File:

PDF, 212 KB

english, 2004

24

The future of model organisms in human disease research

Aitman, Timothy J., Boone, Charles, Churchill, Gary A., Hengartner, Michael O., Mackay, Trudy F. C., Stemple, Derek L.

Journal:

Nature Reviews Genetics

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

25

Use of biochip microarrays to discover genes for dyslipidaemia, insulin resistance and hypertension in rats and humans

Scott, James, Naoumova, Rossi, Shoulders, Carol C., Aitman, Timothy J.

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 113 KB

english, 1999

26

Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins

Catherine A. Martin, Emma Longman, Carol Wooding, Sarah J. Hoosdally, Saira Ali, Timothy J. Aitman, Daniel A.P. Gutmann, Paul S. Freemont, Bernadette Byrne, Kenneth J. Linton

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

27

A high-resolution radiation hybrid map of the proximal region of rat Chromosome 4

Khulood M. Al-Majali, Anne M. Glazier, Penny J. Norsworthy, Faisal N. Wahid, Lisa D. Cooper, Caroline A. Wallace, James Scott, Berthold Lausen, Timothy J. Aitman

Journal:

Mammalian Genome

Year:

1999

Language:

english

File:

PDF, 333 KB

english, 1999

28

F.28. Evidence for Both Quantitative and Qualitative Risk at the FcγR3B Locus in Systemic Lupus Erythematosus (SLE)

David Morris, Amy Roberts, Abi Witherden, John Whittaker, Timothy Aitman, Timothy Vyse

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

29

Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H–Related Protein 5 Deficiency

Katherine A. Vernon, Elena Goicoechea de Jorge, Angela E. Hall, Veronique Fremeaux-Bacchi, Timothy J. Aitman, H. Terence Cook, Robert Hangartner, Ania Koziell, Matthew C. Pickering

Journal:

American Journal of Kidney Diseases

Year:

2012

Language:

english

File:

PDF, 993 KB

english, 2012

30

AP-1 Transcription Factor JunD Confers Protection from Accelerated Nephrotoxic Nephritis and Control Podocyte-Specific Vegfa Expression

H. Terence Cook, Ruth Tarzi, Zelpha D'Souza, Gaelle Laurent, Wei-Chou Lin, Timothy J. Aitman, Fatima Mechta-Grigoriou, Jacques Behmoaras

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

31

Genetic Susceptibility to Experimental Autoimmune Glomerulonephritis in the Wistar Kyoto Rat

John Reynolds, Paul R. Cook, Jacques Behmoaras, Jennifer Smith, Gurjeet Bhangal, Susan Tadros, Jonathan Tee, Alan D. Salama, David J. Evans, Timothy J. Aitman, H. Terence Cook, Charles D. Pusey

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 1.54 MB

english, 2012

32

Glycomics investigation into insulin action

Simon Parry, Dirk Hadaschik, Christine Blancher, Mande K. Kumaran, Natalia Bochkina, Howard R. Morris, Sylvia Richardson, Timothy J. Aitman, Dominique Gauguier, Ken Siddle, James Scott, Anne Dell

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2006

Language:

english

File:

PDF, 1.04 MB

english, 2006

33

Genetics of the metabolic syndrome and implications for therapy

Robert I. Hughes, Timothy J. Aitman

Journal:

International Congress Series

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

34

Molecular genetics of diabetes mellitus

Timothy J. Aitman, John A. Todd

Journal:

Baillière's Clinical Endocrinology and Metabolism

Year:

1995

Language:

english

File:

PDF, 1.68 MB

english, 1995

35

Fatty acids and insulin resistance: A genetic and physiological perspective

Timothy J Aitman

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 135 KB

english, 2000

36

Association of Sirtuin 1 (SIRT1) Gene SNPs and Transcript Expression Levels With Severe Obesity

Stephen J. Clark, Mario Falchi, Bob Olsson, Peter Jacobson, Stéphane Cauchi, Beverley Balkau, Michel Marre, Olivier Lantieri, Johanna C. Andersson, Margareta Jernås, Timothy J. Aitman, Sylvia Richards

Journal:

Year:

2012

Language:

english

File:

PDF, 211 KB

english, 2012

37

JunD/AP1 regulatory network analysis during macrophage activation in a rat model of crescentic glomerulonephritis

Srivastava, Prashant K, Hull, Richard P, Behmoaras, Jacques, Petretto, Enrico, Aitman, Timothy J

Journal:

BMC Systems Biology

Year:

2013

Language:

english

File:

PDF, 940 KB

english, 2013

38

The generation of a library of PCR-analyzed microsatellite variants for genetic mapping of the mouse genome

Cornall, Richard J., Aitman, Timothy J., Hearne, Catherine M., Todd, John A.

Journal:

Year:

1991

Language:

english

File:

PDF, 706 KB

english, 1991

39

PRESERVATIVES IN MILK.

Cornall, Richard J., Aitman, Timothy J., Hearne, Catherine M., Todd, John A.

Journal:

Year:

1902

Language:

english

File:

PDF, 339 KB

english, 1902

40

Familial hypercholesterolaemia: A pressing issue for European health care

Brice, Philippa, Burton, Hilary, Edwards, Christopher W., Humphries, Steve E., Aitman, Timothy J.

Journal:

Atherosclerosis

Year:

2013

Language:

english

File:

PDF, 200 KB

english, 2013

41

Resequencing the susceptibility gene,ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

Roberts, Amy L, Thomas, Ellen RA, Bhosle, Shriram, Game, Laurence, Obraztsova, Olga, Aitman, Timothy J, Vyse, Timothy J, Rhodes, Benjamin

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 505 KB

english, 2014

42

Performance evaluation of Sanger sequencing for the diagnosis of primary hyperoxaluria and comparison with targeted next generation sequencing

Williams, Emma L., Bagg, Eleanor A. L., Mueller, Michael, Vandrovcova, Jana, Aitman, Timothy J., Rumsby, Gill

Journal:

Molecular Genetics & Genomic Medicine

Year:

2015

Language:

english

File:

PDF, 156 KB

english, 2015

43

Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

Thomas, Ellen R. A., Atanur, Santosh S., Norsworthy, Penny J., Encheva, Vesela, Snijders, Ambrosius P., Game, Laurence, Vandrovcova, Jana, Siddiq, Afshan, Seed, Mary, Soutar, Anne K., Aitman, Timothy

Journal:

Molecular Genetics & Genomic Medicine

Year:

2013

Language:

english

File:

PDF, 575 KB

english, 2013

44

Target enrichment and high-throughput sequencing of 80 ribosomal protein genes to identify mutations associated with Diamond-Blackfan anaemia

Gerrard, Gareth, Valgañón, Mikel, Foong, Hui En, Kasperaviciute, Dalia, Iskander, Deena, Game, Laurence, Müller, Michael, Aitman, Timothy J., Roberts, Irene, de la Fuente, Josu, Foroni, Letizia, Karad

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

45

Role of Novel Rat-specific Fc Receptor in Macrophage Activation Associated with Crescentic Glomerulonephritis

Page, Theresa H., D'Souza, Zelpha, Nakanishi, Satoshi, Serikawa, Tadao, Pusey, Charles D., Aitman, Timothy J., Cook, H. Terence, Behmoaras, Jacques

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.54 MB

english, 2012

46

New Insights into the Genetic Control of Gene Expression using a Bayesian Multi-tissue Approach

Petretto, Enrico, Bottolo, Leonardo, Langley, Sarah R., Heinig, Matthias, McDermott-Roe, Chris, Sarwar, Rizwan, Pravenec, Michal, Hübner, Norbert, Aitman, Timothy J., Cook, Stuart A., Richardson, Sylv

Journal:

PLoS Computational Biology

Year:

2010

Language:

english

File:

PDF, 601 KB

english, 2010

47

Mutation of the glucagon receptor gene and diabetes mellitus in the UK: association or founder effect?

Gough, Stephen C.L., Saker, Philip J., Pritchard, Lynn E., Merriman, Tony R., Merriman, Marilyn E., Rowe, Bethan R., Kumar, Sudhesh, Aitman, Timothy, Barnett, Anthony H., Turner, Robert C., Bain, Step

Journal:

Human Molecular Genetics

Year:

1995

Language:

english

File:

PDF, 437 KB

english, 1995

48

Genetic Medicine and Obesity

Aitman, Timothy John

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

49

Adrenal Gland Tumorigenesis after Gonadectomy in Mice Is a Complex Genetic Trait Driven by Epistatic Loci

Bernichtein, Sophie, Petretto, Enrico, Jamieson, Stacey, Goel, Anuj, Aitman, Timothy J., Mangion, Jonathan M., Huhtaniemi, Ilpo T.

Journal:

Year:

2008

Language:

english

File:

PDF, 916 KB

english, 2008

50

Insulin-Like Growth Factor I Gene Expression in the Rat Ovary is Confined to the Granulosa Cells of Developing Follicles

OLIVER, JANE E., AITMAN, TIMOTHY J., POWELL, JOHN F., WILSON, CATHERINE A., CLAYTON, RICHARD N.

Journal:

Year:

1989

Language:

english

File:

PDF, 2.67 MB

english, 1989